Latest News from KDBIO
Ever wondered what cells look like in a hollow fibre bioreactor?
Interesting customer photos in our gallery Example - MSCs form spheroids These polysulfone fibres are around 200µm in diameter with space around the fibres for cells to [...]
Transient or stable expression of monoclonal antibody?
…your decision may depend on cell culture technology The transient expression of monoclonal antibodies is an essential step for early characterization studies but to produce 500 – 1000 mg [...]
How to produce antibodies, cytokines, complex proteins or exosomes for translational research projects
Translational research projects are sometimes hampered by low productivity of an essential cell-secreted agent; this might be, for example, a monoclonal antibody, a cytokine or a more complex recombinant [...]
Amniotic Fluid Stem Cells Extracellular Vesicles – Scalability of Production and Bio-Activity – 3D vs 2D culture
Poster Abstract EV clinical translation is constrained by limitations in scale-up of EVs production. Hollow fiber bioreactors (HFBR) support the culture of large numbers of cells, at high densities, producing [...]
BioBUZZ on FiberCell
BioBUZZ Article about hollow fibre culture of cells "If you’ve worked in cell culture, you’ve surely had experience dealing with tissue culture flasks. These plastic vessels are the staple [...]
FiberCell Applications
The FiberCell Hollow Fibre Bioreactor is a compact system for continuous high cell density culture and is used by academic and commercial labs for scaling up production of mAb, protein, exosomes or virus.
Other applications include antimicrobial PK/PD modelling and cultivation of cells continuously to establish 3D in vitro models.
Compact Hollow Fibre Bioreactor

Maintain >10^9 cells in continuous culture on one shelf of a standard incubator. Single-use hollow fibre cartridge module with built-in gas exchanger.
Productivity example: 500mg – 1000mg mAb in 10 weeks in a volume of only 700ml..
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Hollow fibre cartridge modules

Pre-sterilized, single-use hollow fibre cartridge modules 3ml, 20ml and 70ml, available in 5 kD, 20 kD MWCO. Special 0.1 µm endothelial cell cartridge also available. [learn more].