Lab Scale Hollow Fiber Cell Culture

using a 3D-capillary bioreactor any lab can continuously maintain a very large number of mammalian cells on the shelf of an incubator and produce multiple harvests of supernatant with exceptionally high yields of cell-secreted product

Latest News and Events

U-Cytech Switches to FiberCell for mAb Production

U-CyTech biosciences switches from roller bottles to FiberCell Systems Hollow Fibre Bioreactor U-CyTech biosciences is based in Utrecht, the Netherlands, and produces a wide range of innovative cytokine ELISA, [...]

Meet us at ISEV2021

ISEV2021 provides a great opportunity to discuss 3D CM-EVs production Large amounts of EVs can be obtained from practically any type of cell, including mesenchymal stems cells, maintained over a [...]

New YouTube Channel

New YouTube Channel - Hollow fibre bioreactor technology and applications KDBIO has launched a Youtube channel with short videos to explain hollow fibre bioreactor technology and the advantages this [...]

Publications referring to FiberCell System

Access lists of relevant references / Extracellular vesicles production / Monoclonal antibodies production / Recombinant proteins production / Secretome from 3D cultures

FiberCell Applications

A FiberCell hollow fibre bioreactor is a compact and affordable high cell density culture system aimed at academic and commercial labs that need to produce significant quantities of mAb, protein, exosomes or virus.

Other applications include antimicrobial PK/PD modelling, production of conditioned media, cell secretome, co-culture models, cultivation of cells within fibres under flow and long-term 3D in vitro models (e.g. long term gut model).

Compact Hollow Fibre Bioreactor

Maintain >10^9 cells in continuous culture on one shelf of a standard incubator

CALL US ON :       +44-5603-854-110   or   +33-388-261-286

Monoclonal antibodies

Monoclonal antibody production

Continuous culture of 10^9 hybridomas in a 20ml hollow fibre cartridge on the shelf of a standard incubator [more]

Extracellular vesicles

Extracellular vesicle production

3-Capillary Bioreactor conditions are ideal for continuously culturing MSCs or cell lines and taking repeated harvests of very concentrated EVs [more].

Recombinant proteins

Recombinant protein production

Looking to produce a difficult-to-express protein? A Medium Size hollow fibre cartridge (20ml) can generate 2mg per day over many weeks, even months, with 50 x better yield than traditional static flask culture. [more].

Hollow fibre cartridge modules

Pre-sterilized, single-use hollow fibre cartridge modules 3ml, 20ml and 70ml, available in 5 kD, 20 kD MWCO. Special 0.1 µm endothelial cell cartridge also available. [learn more].

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