Latest News from KDBIO
Transient or stable expression of monoclonal antibody?
…your decision may depend on cell culture technology The transient expression of monoclonal antibodies is an essential step for early characterization studies but to produce 500 – 1000 mg [...]
How to produce antibodies, cytokines, complex proteins or exosomes for translational research projects
Translational research projects are sometimes hampered by low productivity of an essential cell-secreted agent; this might be, for example, a monoclonal antibody, a cytokine or a more complex recombinant [...]
Amniotic Fluid Stem Cells Extracellular Vesicles – Scalability of Production and Bio-Activity – 3D vs 2D culture
Poster Abstract EV clinical translation is constrained by limitations in scale-up of EVs production. Hollow fiber bioreactors (HFBR) support the culture of large numbers of cells, at high densities, producing [...]
BioBUZZ on FiberCell
BioBUZZ Article about hollow fibre culture of cells "If you’ve worked in cell culture, you’ve surely had experience dealing with tissue culture flasks. These plastic vessels are the staple [...]
A549 cells maintained for many weeks in a 20ml hollow fibre bioreactor (5kDa fibres)
Long term culture of A549 cells at high density A compact laboratory hollow fibre culture system provides a convenient way to culture a very large number of cells continuously [...]
FiberCell Applications
The FiberCell Hollow Fibre Bioreactor is a compact system for continuous high cell density culture and is used by academic and commercial labs for scaling up production of mAb, protein, exosomes or virus.
Other applications include antimicrobial PK/PD modelling and cultivation of cells continuously to establish 3D in vitro models.
Compact Hollow Fibre Bioreactor
Maintain >10^9 cells in continuous culture on one shelf of a standard incubator. Single-use hollow fibre cartridge module with built-in gas exchanger.
Productivity example: 500mg – 1000mg mAb in 10 weeks in a volume of only 700ml..
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Hollow fibre cartridge modules
Pre-sterilized, single-use hollow fibre cartridge modules 3ml, 20ml and 70ml, available in 5 kD, 20 kD MWCO. Special 0.1 µm endothelial cell cartridge also available. [learn more].
FiberCell Systems Brochure PDF Download
