High density celline flask culture of hybridomas is made more efficient by completely eliminating serum from both compartments. A serum replacement called CDM-HD or "Chemically-Defined Media for High Density [...]
KDBIO Virtual Exhibition Stand at ECI2021 IN YOUR OWN LAB - produce significant amounts of monoclonal antibodies, recombinant proteins or extracellular vesicles using a FiberCell hollow fibre bioreactor. [...]
In this example, here are the results of the development of monoclonal antibody for 10 newly developed monoclonal cell lines. Following the successful fusion, clone selection and weaning from media [...]
The FiberCell Hollow Fibre Bioreactor is a compact system for continuous high cell density culture and is used by academic and commercial labs for scaling up production of mAb, protein, exosomes or virus.
Continuous culture of 10^9 hybridomas in a 20ml hollow fibre cartridge on the shelf of a standard incubator [more]
Extracellular vesicle production
3-Capillary Bioreactor conditions are ideal for continuously culturing MSCs or cell lines and taking repeated harvests of very concentrated EVs [more].
Recombinant protein production
Looking to produce a difficult-to-express protein? A Medium Size hollow fibre cartridge (20ml) can generate 2mg per day over many weeks, even months, with 50 x better yield than traditional static flask culture. [more].
Hollow fibre cartridge modules
Pre-sterilized, single-use hollow fibre cartridge modules 3ml, 20ml and 70ml, available in 5 kD, 20 kD MWCO. Special 0.1 µm endothelial cell cartridge also available. [learn more].