Long term culture of cartilage organoids

Better oxygen diffusion

Central necrosis of organoids with increasing size can be overcome using a G-Rex culture device with gas permeable membrane at the base . The base gas exchange membrane provides oxygenation to help prevent central necrosis of cartilage organoids. Clinical scale production levels possible, please send us an email enquiry.

REFERENCE :

Manci Li, Juan E. Abrahante, Amanda Vegoe, Yi Wen Chai, Beth Lindborg, Ferenc Toth, Peter A. Larsen, Timothy D. O’Brien Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids
doi: https://doi.org/10.1101/2021.09.21.461213

G-Rex 6 Plate

G-Rex 6 Well Plate

10cm2 gas exchange membrane per well

G-Rex 100M

100cm2 gas exchange membrane

Scale-up 

Clinical scale production levels possible, please send us an email enquiry.