G-Rex® 6M Culture Plates

Easily expand T-Cells, NK Cells, HSC – no media change required

Primary application  :

  • Cell and gene-modified cell research and manufacturing process development
  • Allows activation, transduction, and expansion
  • Process development protocols directly scale up to clinical doses in larger G-Rex® bioreactors

Gas permeable membrane surface area per well
= 10 cm2

Media volume per well
= 100 ml

Cat.# 80660M

Expand 5 million non-adherent cells (such as T cells, NK cells, HSC) per well into up to 400 million cells per well in 7 to 10 days with no need for medium exchange.

Expand 2.5 million cells into between 150 to 200 million cells in about 10 days with NO medium exchange..

Gas permeable membrane surface area per well
= 5 cm2

Media volume per well
= 50 ml

Cat.# 80300M

Expand 1 million non-adherent cells per well into up to 60 – 80 million cells per well in 7 to 10 days with no need for medium exchange.

Gas permeable membrane surface area per well
= 2 cm2

Media volume per well
= 20 ml

Cat.# 80120M

Poster/Publication Download :

Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. https://pubmed.ncbi.nlm.nih.gov/34788079/

Generation of non-human primate CAR Tregs using artificial antigen-presenting cells, simian tropic lentiviral vectors, and antigen-specific restimulation https://pubmed.ncbi.nlm.nih.gov/36386869/

Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells https://pubmed.ncbi.nlm.nih.gov/34997202/

Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocyteshttps://pubmed.ncbi.nlm.nih.gov/38022678/

Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistencehttps://pmc.ncbi.nlm.nih.gov/articles/PMC11063605/

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Precision Oncology Research News

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