G-Rex® Culture Plates and Bioreactors
Easily expand T-Cells and NK Cells – with no media change required
Primary application :
- Cell and gene-modified cell research and manufacturing process development
- Allows activation, transduction, and expansion
- Process development protocols directly scale up to clinical doses in larger G-Rex® bioreactors
Gas permeable membrane surface area per well
= 10 cm2
Media volume per well
= 100 ml
Cat.# 80660M
Expand 5 million non-adherent cells (such as T cells, NK cells, HSC) per well into up to 400 million cells per well in 7 to 10 days with no need for medium exchange.
— EU distributor : G-Rex® range of culture products —
https://www.wilsonwolf.com/product-and-order-info/
KDBIO provides quotes in Euros to cover all import tariffs and costs associated with international shipping of products from WilsonWolf Manufacturing LLC (USA)
G-Rex®100M Open System R.U.O., Cat.# RU81100
100cm² gas permeable membrane surface with 1000 mL media capacity. Expand 50 million cells into between 2 to 4 billion cells in about 10 days with NO medium exchange. [GAMMA IRRADIATED. For non-clinical, non-therapeutic, research use only.]
THE MANUFACTURER MAKES NO CLAIMS REGARDING THE PERFORMANCE OF THESE PRODUCTS FOR CLINICAL TREATMENT OR THERAPEUTIC APPLICATIONS.
G-Rex® Products List
| Part Number | Description |
|---|---|
| 80000E | GatheRex Liquid Handling, Cell Harvest Pump |
| 80000Z | GatheRex Liquid Handling, Cell Harvest Pump |
| 80040S | G-Rex®10 Open System, Sterile Fluid Path |
| 80055 | G-Rex®5M Open System, Sterile Fluid Path |
| 80110 | G-Rex®10M Open System, Sterile Fluid Path |
| 80110-CS | G-Rex®10M-CS (closed system), Sterile Fluid Path |
| 80110S | G-Rex®10M Open System, Research Use Only |
| 80110S-CS | G-Rex®10M-CS (closed system), Research Use Only |
| 80120M | G-Rex®6M – 2cm² Well Plate |
| 80192M | G-Rex®24 Well Plate |
| 80240M | G-Rex®6 Well Plate |
| 80300M | G-Rex®6M – 5cm² Well Plate |
| 80500 | G-Rex®100 Open System, Sterile Fluid Path |
| 80660M | G-Rex®6M Well Plate |
| 81100 | G-Rex®100M Open System, Sterile Fluid Path |
| 81100-CS | G-Rex®100M-CS (closed system), Sterile Fluid Path |
| G285500 | G-Rex®500M Open System, Sterile Fluid Path |
| G285500-CS | G-Rex®500M-CS (closed system), Sterile Fluid Path |
| G285500-RU | G-Rex®500M Open System, Research Use Only |
| G285500-TF | G-Rex®500M-TF (closed system with open access), Sterile Fluid Path |
| RU80055 | G-Rex®5M Open System, Research Use Only |
| RU80550 | G-Rex®50M Open System, Research Use Only |
| RU80550-CS | G-Rex®50M-CS (Closed System), Research Use Only |
| RU80550-TF | G-Rex®50M-TF (closed system with open access), Research Use Only |
| RU81100 | G-Rex®100M Open System, Research Use Only |
| RU81100-CS | G-Rex®100M-CS (closed system), Research Use Only |
| RU85500-TF | G-Rex®500M-TF (closed system with open access), Research Use Only |
| RUO5500-CS | G-Rex®500M-CS (closed system), Research Use Only |
| WW-FP250ML | G-Rex 250mL Processing Bag |
| WW-SV1L444 | G-Rex 1L Processing Bag |
| WW-SV5L844N | G-Rex 5L Processing Bag |
Poster/Publication Download :
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. https://pubmed.ncbi.nlm.nih.gov/34788079/
Generation of non-human primate CAR Tregs using artificial antigen-presenting cells, simian tropic lentiviral vectors, and antigen-specific restimulation https://pubmed.ncbi.nlm.nih.gov/36386869/
Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells https://pubmed.ncbi.nlm.nih.gov/34997202/
Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocyteshttps://pubmed.ncbi.nlm.nih.gov/38022678/
Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistencehttps://pmc.ncbi.nlm.nih.gov/articles/PMC11063605/
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