G-Rex® 6M Culture Plates

Easily expand T-Cells, NK Cells, HSC – no media change required

Primary application  :

  • Cell and gene-modified cell research and manufacturing process development
  • Allows activation, transduction, and expansion
  • Process development protocols directly scale up to clinical doses in larger G-Rex® bioreactors

Gas permeable membrane surface area per well
= 10 cm2

Media volume per well
= 100 ml

Cat.# 80660M

Expand 5 million non-adherent cells (such as T cells, NK cells, HSC) per well into up to 400 million cells per well in 7 to 10 days with no need for medium exchange.

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Expand 2.5 million cells into between 150 to 200 million cells in about 10 days with NO medium exchange..

G-Rex culture plate

Gas permeable membrane surface area per well
= 5 cm2

Media volume per well
= 50 ml

Cat.# 80300M

Expand 1 million non-adherent cells per well into up to 60 – 80 million cells per well in 7 to 10 days with no need for medium exchange.

Gas permeable membrane surface area per well
= 2 cm2

Media volume per well
= 20 ml

Cat.# 80120M

Poster/Publication Download :

Determining Optimal Seeding Density for Human T-Cell Expansion in G-Rex

Optimizing the production of suspension cells using the G-Rex “M” series

Streamlined production of genetically modified T cells with activation, transduction and expansion in closed-system GRex bioreactors

Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. https://pubmed.ncbi.nlm.nih.gov/34788079/

Generation of non-human primate CAR Tregs using artificial antigen-presenting cells, simian tropic lentiviral vectors, and antigen-specific restimulation https://pubmed.ncbi.nlm.nih.gov/36386869/

Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells https://pubmed.ncbi.nlm.nih.gov/34997202/

Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocyteshttps://pubmed.ncbi.nlm.nih.gov/38022678/

Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistencehttps://pmc.ncbi.nlm.nih.gov/articles/PMC11063605/

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Easily expand T-Cells and NK-Cells to high numbers

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Functional Precision Oncology Research News

Increase spheroid replicates without extra pipetting KDK096 SP5D 96-Well Plate (25 spheroids per well) The Advantage of SP5D Patient-Derived Tumor Organoids and Multicellular Tumor Spheroids Patient derived tumoroids and tumour spheroids provide [...]