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4th Next-Gen Immuno-Oncology Congress, London, March 12-13th

Meet KDBIO at the 4th Annual MarketsandMarkets Next Gen Immuno-Oncology Congress to discuss production of "difficult-to-express" mAbs and other proteins using continuous high density cell culture for more "in-vivo like" culture conditions. https://events.marketsandmarkets.com/4th-annual-marketsandmarkets-next-gen-immuno-oncology-congress/

By |2021-02-04T08:35:13+00:00January 6th, 2020|Events|0 Comments

ECCMID, April 18th – 21st, Paris

ECCMID 2020, Paris Come to the KDBIO booth at ECCMID to discuss the hollow fibre system for: 1) precise in-vitro modelling of human PK and analysis of pharmacodynamics as well as following the development of resistance over time and in response to different drug combination treatments 2) Efficient production of mAb and rec. proteins [...]

By |2021-02-04T08:35:16+00:00January 4th, 2020|Events|0 Comments

New Publication – Exosomes from ucMSCs – Osteochondral Regeneration

Exosomes produced from 3D cultures of umbilical cord mesenchymal stem cells in a hollow-fiber bioreactor show improved osteochondral regeneration activity Abstract: Animal and clinical studies have shown that mesenchymal stem cells (MSCs) play an important role in cartilage repair. The therapeutic effect of mesenchymal stem cells based therapies has been increasingly demonstrated to exosome-mediated paracrine [...]

By |2021-02-04T08:35:16+00:00January 4th, 2020|News|0 Comments

In vitro PK/PD – new publication from FDA – drug combos – E. coli CFT073

The Effect of Drug Combinations on the Kinetics of the Emergence of Antibiotic Resistance in E. coli CFT073 Using the In Vitro Hollow Fiber Infection Model Abstract: Antibiotic resistance is one of the major threats to public health today. To address this problem requires an urgent comprehensive approach. Strategic and multi-targeted combination therapy [...]

By |2021-02-04T08:35:17+00:00January 4th, 2020|News|0 Comments

In vitro PK/PD – New publication in “Cryptosporidium”

In Vitro Culture of Cryptosporidium parvum Using Hollow Fiber Bioreactor: Applications for Simultaneous Pharmacokinetic and Pharmacodynamic Evaluation of Test Compounds Abstract: Hollow fiber technology is a powerful tool for the culture of difficult-to-grow cells. Cryptosporidium parvum has a multistage sexual and asexual life cycle that has proved difficult to culture by conventional in vitro [...]

By |2021-02-04T08:35:17+00:00January 4th, 2020|News|0 Comments

British Society for Immunology Congress 2019

KDBIO exhibition booth at BSI 2019, Liverpool Thanks to the immunologists who stopped at the KDBIO booth during BSI 2019 to discuss their future in-house projects for production of cytokines, recombinant vaccines, monoclonal antibodies and exosomes. The FiberCell bioreactor is ideal for immunology labs wanting to generate monoclonal antibody in the range 100 mg [...]

By |2021-02-04T08:35:17+00:00January 4th, 2020|Events|0 Comments

GSEV/ASEV Joint Autumn Meeting 2019

Interested in producing EVs from cells in continuous high density culture? Meet us in Freising. KDBIO will be showing the FiberCell hollow fibre bioreactor and available to discuss the latest information about growing cells around porous fibres that are dynamically perfused with media. In this mode of culture EVs are retained and concentrated by [...]

By |2021-02-04T08:35:17+00:00November 13th, 2019|Events|0 Comments

New publication – glycosylated protein production

Publication refers to use of FiberCell Bioreactor : Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions. "PSG1‐Fc, PSG1‐His, PSG1N‐Fc and the proteins used interchangeably as negative controls, Fc and CEACAM9‐Fc, were generated from the supernatant of stably transfected CHO‐K1 single‐cell clones established in our laboratory and grown in [...]

By |2021-02-04T08:35:17+00:00November 12th, 2019|News|0 Comments

GEIVEX – Granada, Spain 6 & 7th November 2019

KDBIO exhibiting at GEIVEX 2019 in Granada Large amounts of EVs can be obtained from practically any type of cell, including mesenchymal stems cells, maintained over a few weeks at high density in a FiberCell Hollow Fibre Bioreactor. A medium size 20ml hollow fibre cartridge (C2011) permits periodic collection of 20mls of exosome-enriched [...]

By |2021-02-04T08:35:17+00:00October 29th, 2019|Events|0 Comments
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