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Large scale production of parasites using a FiberCell Hollow Fibre Bioreactor

Two recent examples: Continuous culture of Cryptosporidium parvum using hollow fiber technology: Morada, M. et al.; Int J Parasitol. 2016 Jan;46(1):21-9 [related presentation PDF] See also: in vitro gut model Babesia bigemina: Advances in continuous in vitro culture using serum-free medium supplemented with insulin, transferrin, selenite, and putrescine: Rojas-Martinez, C. et al.; Parisitology International 67 [...]

By | December 28th, 2018|News|0 Comments

GSEV2018 – KDBIO presentation : “Efficient production of extracellular vesicles”

KDBIO sponsored the GSEV2018 meeting in Marburg (15-16 November 2018) and presented the FiberCell Hollow Fibre Bioreactor for generating large amounts of EVs in much smaller volumes of supernatant than is possible with monolayer culture. Download the presentation PDF here: High efficiency production of exosomes / EVs

By | November 19th, 2018|Events, News|0 Comments

The Advantage of Hollow Fiber Bioreactors

Have you ever wondered about all the applications possible for a laboratory hollow fibre bioreactor and what advantages you could expect compared to traditional cell culture methods? Look no further - here's a free e-book introduction to hollow fibre bioreactor technology.

By | October 28th, 2018|News|0 Comments

European Congress of Immunology, Amsterdam, 2018

KDBIO sponsored the ECI2018 in Amsterdam 3/9/18 - 5/9/18 and participated with an exhibition booth. Thanks to everyone who came to see us! We had many interesting conversations with vistors about using the FiberCell hollow fibre bioreactor to achieve faster more convenient production of mAbs, recombinant proteins and exosomes. Several discussions about generating sigificant amounts [...]

By | September 9th, 2018|Events|0 Comments

Cellulosic hollow fibre cartridges – when should these be used in PK/PD studies?

Cellulosic hollow fibre cartridges are used in PK/PD applications when issues with compound binding to polysulfone fibres are detected. One well-known pharmaceutical company put in place the procedure below to check fibre compatability with each new compound prior to PK/PD studies. If you would like to receive this information as a PDF file please ask: [...]

By | July 7th, 2018|News|0 Comments

FiberCell Systems Inc. present at ISEV2018

Thanks to all the visitors who came to speak with us at the exhibition stand during ISEV2018 meeting. EV production with the FiberCell Hollow Fibre Bioreactor offers several major advantages: Continuously maintain a huge number of cells in a compact 3D culture system Periodically collect large amounts of clean, concentrated EVs Unit fits on a [...]

By | May 14th, 2018|Events, News|0 Comments

GEN Tutorial : Hollow Fibers Enhance Protein Expression

Are you looking to produce fully biologically active human recombinant protein? Do you need 100mg to 1g produced in mammalian cells but don't want to outsource? This article by John Cadwell of FiberCell Systems was written with your project in mind...https://www.genengnews.com/gen-articles/hollow-fibers-enhance-protein-expression/6303

By | April 15th, 2018|News|0 Comments

KDBIO sponsors “Extracellular Vesicles: From Biology to Biomedical Applications” – EMBO Practical Course

KDBIO will be present on 12th April during this EMBO Practical Course to present the FiberCell Hollow Fibre Bioreactor as an efficient way to produce large quantities of concentrated exosomes, serum-free. Course Overview : A rapidly increasing number of researchers aim to purify and identify extracellular vesicles and many methodologies to isolate and analyse these [...]

By | March 29th, 2018|News|0 Comments

KDBIO sponsors the London Stem Cell Network’s 2018 Symposium (26th February 2018)

The London Stem Cell Network is a platform for all London research groups working in this area across all London Universities and Institutes. It is organised by representatives of the Francis Crick Institute, Imperial College London, King's College London and University College London. https://lscn.crick.ac.uk/

By | February 18th, 2018|News|0 Comments

New Article : Any Lab Can Now Very Efficiently Express Recombinant Proteins in Mammalian Cells

For any lab that needs to scale up production of "difficult-to-express" recombinant protein, for example complex, multi-subunit proteins required well folded, assembled and glycosylated in 100's of milligrams, a FiberCell hollow fiber bioreactor offers a very efficient solution. This new article by John Cadwell, founder of FiberCell Systems Inc., explains why. Also please visit our [...]

By | December 28th, 2017|News|0 Comments