For any lab that needs to scale up production of "difficult-to-express" recombinant protein, for example complex, multi-subunit proteins required well folded, assembled and glycosylated in 100's of milligrams, a FiberCell hollow fiber bioreactor offers a very efficient solution. This new article by John Cadwell, founder of FiberCell Systems Inc., explains why. Also please visit our [...]
...Hollow fiber bioreactors (HFBR) offer significant advantages over flask culture, especially for the collection and concentration of exosomes under 3D physiologic cell culture conditions (Download Article). See recent customer publications here.
KDBIO is a sponsor of the UKEV meeting on December 12th at the University of Birmingham and will particpate with an exhibition stand and a talk on the topic of efficient production of EVs. https://www.birmingham.ac.uk/facilities/mds-cpd/conferences/ukev/index.aspx
KDBIO will participate at the French Society for Extracellular Vesicles on 6th and 7th November 2017. The FiberCell hollow fibre bioreactor provides a compact and efficient means to generate concentrated EVs in large quantity from cells maintained under extremely high density. Different cartridge modules are available to suit the scale of the project. Meeting website [...]
This new article by John Cadwell, President and CEO of FiberCell Systems Inc., points out the specific advantages of hollow fibre bioreactors for monoclonal antibody production. Production of Monoclonal Antibodies from Hybridomas in a Hollow Fiber Bioreactor Hollow fibre systems provide cultured cells with a porous support matrix in place of the solid, impermeable plastic [...]
"Clinical Scale Production and Wound Healing Activity of Human Adipose Derived Mesenchymal Stem Cell Extracellular Vesicles from a Hollow Fiber Bioreactor" Download PDF : Fibercell Poster ISEV2017 Interested in more efficient production of exosomes? The FiberCell hollow fibre bioreactor enables continuous production of concentrated EVs over periods of weeks from all kinds of cell types. [...]
Thanks to Dr. Lim and team for this fascinating video.
One billion cells or more can be cultured over long periods in a 20 ml FiberCell hollow fibre bioreactor. This customer review describes how the system is used for harvesting large amounts of recombinant protein. The same principles apply for harvesting any factors secreted by mammalian cells. N.B. the 70 ml FiberCell cartridges enable up [...]
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